Restructuring - Additional Information (Details) $ in Thousands			3 Months Ended		9 Months Ended
	May 31, 2023 USD ($)	Nov. 30, 2022 USD ($)	Sep. 30, 2022 USD ($)	Sep. 30, 2021 USD ($)	Sep. 30, 2022 USD ($)	Sep. 30, 2021 USD ($)	Dec. 31, 2021 USD ($) Employee
Restructuring Cost and Reserve [Line Items]
Restructuring Charges			$ (152)	$ 0	$ 11,697	$ 0
Employee related termination costs					8,600
Lease impairment expense					600
Contract termination fees			2,500		2,500
Outstanding Accrued Expense			1,000		1,000
Common stock to be issued			$ 43		43		$ 32
Performance-Based Awards [Member]
Restructuring Cost and Reserve [Line Items]
Compensation expense recognized					$ 500
Human Capital Management Committee [Member] | Subsequent Event [Member]
Restructuring Cost and Reserve [Line Items]
Aggregate Retention Awards Cash Bonus	$ 3,400	$ 1,100
Cash	900	300
Tebipenem HBr Program [Member]
Restructuring Cost and Reserve [Line Items]
Number Of Employees Before Restructuring Initiative | Employee							146
Number Of Employees After Restructuring Initiative | Employee							41
Executive Retention Awards Member | Subsequent Event [Member]
Restructuring Cost and Reserve [Line Items]
Cash Bonus		$ 900
Common stock to be issued	$ 1,700