Common Stock - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands	1 Months Ended			3 Months Ended		9 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Feb. 28, 2021	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021	Dec. 31, 2021	Aug. 17, 2021	Mar. 11, 2021
Class Of Stock [Line Items]
Common stock, shares authorized				120,000,000		120,000,000		120,000,000
Issuance of stock, value				$ 6,128	$ 1,105	$ 10,331	$ 5,357
Proceeds from sale of common stock to related party						$ 10,334	$ 5,357
Series C Preferred Stock [Member]
Class Of Stock [Line Items]
Preferred stock, conversion basis			73
Number of shares issuable upon conversion			73,000
Series B Convertible Preferred Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares	938		62
Number of shares issuable upon conversion	938,000		62,000
Series C Convertible Preferred Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares						2,214
Number of shares issuable upon conversion				2,214,000		2,214,000
Series D Preferred Stock [Member]
Class Of Stock [Line Items]
Preferred stock, conversion basis	942,000					2,273,000
Number of shares issuable upon conversion	942,000			2,273,000		2,273,000
Common Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares				3,226,859	70,000	3,964,478	327,185
Issuance of stock, value				$ 4		$ 5	$ 1
Maximum [Member]
Class Of Stock [Line Items]
Common stock, shares authorized									120,000,000
Minimum [Member]
Class Of Stock [Line Items]
Common stock, shares authorized									60,000,000
Pfizer Inc Member
Class Of Stock [Line Items]
Issuance of stock, shares			2,362,348
Issuance of stock, value			$ 27,500
Pfizer Purchase Agreement [Member]
Class Of Stock [Line Items]
Issuance of stock, value			$ 12,500
Pfizer Purchase Agreement [Member] | Pfizer Inc Member
Class Of Stock [Line Items]
Issuance of stock, shares		2,362,348
Share price		$ 16.93
Proceeds from sale of common stock to related party		$ 40,000
At-The-Market Offering Program [Member]
Class Of Stock [Line Items]
Proceeds from sale of common stock to related party						$ 10,700
At-The-Market Offering Program [Member] | Common Stock [Member]
Class Of Stock [Line Items]
Issuance of stock, shares						3,964,478
Share price				$ 2.69		$ 2.69
At-The-Market Offering Program [Member] | Sales Agreement [Member] | Cantor Fitzgerald & Co [Member] | Maximum [Member]
Class Of Stock [Line Items]
Authorized offering value										$ 300,000
Common stock available for issuance										$ 75,000