Share-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2022

Share Based Compensation Arrangement By Share Based Payment Award [Line Items]

Summary of Stock Option Activity

The following table summarizes stock option activity under all equity plans (excluding RSUs) during the nine months ended September 30, 2022:

	Number of Shares			Weighted Average Exercise Price		Weighted Average Contractual Term		Aggregate Intrinsic Value
						(in years)		(in thousands)
Outstanding as of December 31, 2021		4,890,716		$	11.75		7.62	$	24,263
Granted		956,604			11.12
Exercised		(56,120	)		7.48
Forfeited or cancelled		(1,775,539	)		13.23
Outstanding as of September 30, 2022		4,015,661		$	11.00		5.48	$	2
Outstanding as of September 30, 2022 - vested and    expected to vest		4,015,661		$	11.00		5.48	$	2
Exercisable at September 30, 2022		2,606,480		$	9.65		4.73	$	—

Summary of Activity of Options and RSUs of Performance-Based Options

he following table summarizes RSU activity under all equity plans during the nine months ended September 30, 2022:

	Number of RSU Shares			Weighted Average Grant Date Fair Value
Outstanding as of December 31, 2021		513,690			17.08
Granted		1,115,357			7.01
Vested and released		(75,287	)		17.07
Forfeited or cancelled		(408,000	)		14.16
Outstanding as of September 30, 2022		1,145,760			8.32

Summary of Share-Based Compensation Expense

The Company recorded share-based compensation expense related to incentive stock options, nonqualified stock options, stock grants, and stock-based awards in the following expense categories of its consolidated statements of operations and comprehensive loss (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2022		2021		2022		2021
Research and development expenses	$	730	$	1,059	$	2,595	$	2,794
General and administrative expenses		1,376		1,271		4,031		3,708
Total	$	2,106	$	2,330	$	6,626	$	6,502