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Share-Based Compensation - Summary of Assumptions Used to Determine Fair Value of Stock Option Awards Granted to Employees and Directors (Detail)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Share-based Payment Arrangement [Abstract]    
Risk-free interest rate 0.80% 1.10%
Expected term (in years) 6 years 2 months 12 days 6 years 2 months 12 days
Expected volatility 92.60% 82.70%
Expected dividend yield 0.00% 0.00%