CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Revenues:
Grant revenue	$ 15,186	$ 9,072
Collaboration revenue	$ 3,070	$ 258
Type of Revenue [Extensible List]	License [Member]	License [Member]
Total revenues	$ 18,256	$ 9,330
Operating expenses:
Research and development	64,526	67,003
General and administrative	41,701	21,440
Total operating expenses	106,227	88,443
Loss from operations	(87,971)	(79,113)
Other income (expense):
Interest income	346	401
Other income (expense), net	(395)	432
Interest expense related to the sale of future royalties	(1,940)
Change in fair value of derivative liability	204
Total other income (expense), net	(1,785)	833
Net loss	$ (89,756)	$ (78,280)
Net loss per share attributable to common stockholders, basic and diluted	$ (2.91)	$ (3.52)
Weighted average common shares outstanding, basic and diluted:	30,895,756	22,386,122
Comprehensive loss:
Net loss	$ (89,756)	$ (78,280)
Other comprehensive gain (loss):
Unrealized gain (loss) on marketable securities	5	(23)
Net unrealized gains (losses) on securities	5	(23)
Total comprehensive loss	$ (89,751)	$ (78,303)