CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 112,584	$ 85,209
Marketable securities	33,818	41,697
Other receivables	2,280	5,330
Tax incentive receivable, current	361	846
Prepaid expenses and other current assets	8,829	6,063
Total current assets	157,872	139,145
Property and equipment, net	1,026	1,669
Tax incentive receivable		311
Operating lease right-of-use assets	6,530	7,114
Other assets	5,644	5,212
Total assets	171,072	153,451
Current liabilities:
Accounts payable	1,101	1,155
Accrued expenses and other current liabilities	14,350	12,241
Operating lease liabilities	1,362	947
Deferred Revenue, Current	1,857
Derivative liability	802
Total current liabilities	18,670	14,343
Liability related to the sale of future royalties	48,414
Non-current operating lease liabilities	5,973	6,891
Deferred revenue, non-current	8,786
Other long-term liabilities	138	177
Total liabilities	82,783	21,411
Commitments and contingencies (Note 12)
Stockholders' equity:
Preferred stock, $0.001 par value; 10,000,000 shares authorized, 3,218,287 shares issued and outstanding as of December 31, 2020 and 2,720 shares issued and outstanding as of December 31, 2019	3	3
Common stock, $0.001 par value; 60,000,000 shares authorized as of December 31, 2020 and December 31, 2019; 29,260,247 shares issued and outstanding as of December 31, 2020 and 19,190,695 shares issued and outstanding as of December 31, 2019	32	29
Additional paid-in capital	455,719	409,722
Accumulated deficit	(367,463)	(277,707)
Accumulated other comprehensive gain (loss)	(2)	(7)
Total stockholders' equity	88,289	132,040
Total liabilities and stockholders' equity	$ 171,072	$ 153,451