LICENSE AGREEMENT - Miami University (Details) - USD ($)			12 Months Ended
	Dec. 14, 2020	Oct. 28, 2020	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Agreements
Research and development			$ 55,634,000	$ 62,570,000
General and administrative			27,316,000	43,048,000
Operating expenses			82,950,000	105,618,000
Accrued expenses and other current liabilities			14,756,000	16,559,000
2020 license agreement | University of Miami
Agreements
Amount of first payment to be made for license issue fee		$ 1,100,000
Amount of second payment to be made for license issue fee, due on first anniversary of the date of license		500,000
Payment to be made on achievement of specified patenting and development milestones		2,200,000
Payment to be made on achievement of late stage regulatory milestones		$ 4,100,000
Agreement term		10 years
Written notice period for termination of agreement		60 days
Written notice period of material breach leading to termination		60 days
Research and development			100,000	30,000.00
General and administrative			0	0
Accrued expenses and other current liabilities			$ 300,000	300,000
2020 license agreement | University of Miami | Minimum
Agreements
Royalties payment (as a percent)		0.88%
Non-royalty sublicensing revenue payment (as a percent)		15.00%
2020 license agreement | University of Miami | Maximum
Agreements
Royalties payment (as a percent)		5.00%
Non-royalty sublicensing revenue payment (as a percent)		25.00%
2020 research agreement and amendment | University of Miami
Agreements
Consideration	$ 300,000
Research and development				48,000	$ 200,000
Accrued expenses and other current liabilities				$ 1,000,000.0	$ 200,000