ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES
Accrued pre-clinical and clinical expenses	$ 9,912	$ 13,742
Short-term insurance financing note	789	1,074
Accrued professional fees	419	511
Accrued compensation and benefits	2,779	2,103
Accrued commercial expenses	1,394	502
Accrued patent expenses	279	1,704
Other	987	553
Total accrued expenses & other current liabilities	$ 16,559	$ 20,189