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Condensed Statements of Cash Flows - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
OPERATING ACTIVITIES:    
Net loss $ (78,425) $ (70,272)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 8,328 5,471
Amortization of operating lease right-of-use assets 308 281
Change in operating lease liability (299) (263)
Changes in operating assets and liabilities:    
Financed insurance premium (4,434)  
Prepaid expenses (1,107) 3,396
Accounts payable 8,530 (6,739)
Accrued expenses and other current liabilities 149 11,127
Amortization of leasehold improvements 1  
Amortization of insurance premium 3,163 1,540
Net cash used in operating activities (63,786) (55,459)
INVESTING ACTIVITIES:    
Purchase of available-for-sale securities (109,119) (127,558)
Proceeds from sale of available-for-sale securities 5,539 17,109
Proceeds from maturities of available-for-sale securities 104,206 62,536
Net cash used in investing activities 626 (47,913)
FINANCING ACTIVITIES:    
Proceeds from stock issuance, net of cash issuance costs 74,420 134,102
Proceeds from financed insurance premium 4,434  
Financed insurance premium down payment   (793)
Repayments of short-term borrowings (3,534) (1,074)
Exercise of stock options for common stock under Equity Incentive Plan 512 1,665
Exercise of Warrants 69  
Net cash provided by financing activities 75,901 133,201
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS 12,741 29,829
Cash and cash equivalents at beginning of period 57,466 18,850
Cash and cash equivalents at end of period 70,207 48,679
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:    
Insurance premium obtained in exchange for a short-term loan   (4,015)
Unrealized gain (loss) on marketable securities $ (142) 92
Private Placement    
FINANCING ACTIVITIES:    
Payment of offering costs   (206)
Registration of Form S-3 offering/Shelf Offering    
FINANCING ACTIVITIES:    
Payment of offering costs   (493)
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:    
Stock issuance costs in accrued expenses   $ 2