The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108   3,801,950 42,305 SH   SOLE   42,305 0 0
AFFIMED N V COM N01045108   886,064 560,800 SH   SOLE   560,800 0 0
AGILE THERAPEUTICS INC COM 00847L100   1,323,866 711,756 SH   SOLE   711,756 0 0
ALBIREO PHARMA INC COM 01345P106   1,277,335 78,029 SH   SOLE   78,029 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206   14,016,248 3,504,062 SH   SOLE   3,504,062 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   24,096,908 899,474 SH   SOLE   899,474 0 0
AQUESTIVE THERAPEUTICS INC COM 03843E104   657,000 300,000 SH   SOLE   300,000 0 0
ARTARA THERAPEUTICS INC COM 04300J107   746,994 32,478 SH   SOLE   32,478 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101   31,023,379 275,494 SH   SOLE   275,494 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   15,744,928 352,551 SH   SOLE   352,551 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100   1,257,978 210,013 SH   SOLE   210,013 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103   15,084,744 7,542,372 SH   SOLE   7,542,372 0 0
BIODELIVERY SCIENCES INTL IN COM 09060J106   465,041 122,702 SH   SOLE   122,702 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105   3,620,282 106,385 SH   SOLE   106,385 0 0
CHEMOCENTRYX INC COM 16383L106   23,304,842 580,011 SH   SOLE   580,011 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108   1,938,369 580,350 SH   SOLE   580,350 0 0
CYCLERION THERAPEUTICS INC COM 23255M105   893,434 337,145 SH   SOLE   337,145 0 0
CYTOKINETICS INC COM NEW 23282W605   2,142,243 181,700 SH   SOLE   181,700 0 0
DANAHER CORPORATION COM 235851102   32,419,197 233,957 SH   SOLE   233,957 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101   17,047,715 414,081 SH   SOLE   414,081 0 0
DEXCOM INC COM 252131107   5,260,728 19,537 SH   SOLE   19,537 0 0
DICERNA PHARMACEUTICALS INC COM 253031108   1,098,048 59,774 SH   SOLE   59,774 0 0
EHEALTH INC COM 28238P109   444,005 3,153 SH   SOLE   3,153 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105   474,014 69,708 SH   SOLE   69,708 0 0
ENSIGN GROUP INC COM 29358P101   13,444,688 357,028 SH   SOLE   357,028 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104   1,631,627 109,212 SH   SOLE   109,212 0 0
FATE THERAPEUTICS INC COM 31189P102   6,784,822 305,485 SH   SOLE   305,485 0 0
GENMARK DIAGNOSTICS INC COM 372309104   2,159,939 524,257 SH   SOLE   524,257 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105   19,855,305 510,571 SH   SOLE   510,571 0 0
HCA HEALTHCARE INC COM 40412C101   9,074,850 101,000 SH   SOLE   101,000 0 0
HESKA CORP COM RESTRC NEW 42805E306   1,148,636 20,771 SH   SOLE   20,771 0 0
IGM BIOSCIENCES INC COM 449585108   548,586 9,770 SH   SOLE   9,770 0 0
IMMUNOVANT INC COM 45258J102   1,196,419 76,866 SH   SOLE   76,866 0 0
INFLARX NV COM N44821101   746,764 195,488 SH   SOLE   195,488 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100   2,695,557 90,047 SH   SOLE   90,047 0 0
KADMON HLDGS INC COM 48283N106   4,086,717 975,350 SH   SOLE   975,350 0 0
LIQUIDIA TECHNOLOGIES INC COM 53635D202   1,152,240 244,637 SH   SOLE   244,637 0 0
MACROGENICS INC COM 556099109   535,428 91,998 SH   SOLE   91,998 0 0
MODEL N INC COM 607525102   8,312,848 374,284 SH   SOLE   374,284 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100   3,986,160 146,550 SH   SOLE   146,550 0 0
MYOKARDIA INC COM 62857M105   1,301,014 27,752 SH   SOLE   27,752 0 0
OTONOMY INC COM 68906L105   1,106,622 561,737 SH   SOLE   561,737 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103   1,594,507 172,193 SH   SOLE   172,193 0 0
PENNANT GROUP INC COM 70805E109   3,995,683 282,181 SH   SOLE   282,181 0 0
PFENEX INC COM 717071104   408,304 46,293 SH   SOLE   46,293 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107   491,638 58,251 SH   SOLE   58,251 0 0
RADIUS HEALTH INC COM NEW 750469207   3,913,949 301,073 SH   SOLE   301,073 0 0
SANOFI SPONSORED ADR 80105N105   8,288,350 189,578 SH   SOLE   189,578 0 0
SCPHARMACEUTICALS INC COM 810648105   979,901 132,419 SH   SOLE   132,419 0 0
SESEN BIO INC COM 817763105   728,780 1,300,000 SH   SOLE   1,300,000 0 0
TARO PHARMACEUTICAL INDS LTD SHS M8737E108   4,679,291 76,459 SH   SOLE   76,459 0 0
TELIGENT INC NEW COM 87960W104   1,081,613 3,862,903 SH   SOLE   3,862,903 0 0
TG THERAPEUTICS INC COM 88322Q108   24,217,588 2,461,137 SH   SOLE   2,461,137 0 0
XENON PHARMACEUTICALS INC COM 98420N105   811,842 71,591 SH   SOLE   71,591 0 0
ZOGENIX INC COM NEW 98978L204   49,793,039 2,013,467 SH   SOLE   2,013,467 0 0
AIR LEASE CORP CL A 00912X302   442,800 20,000 SH Put SOLE   20,000 0 0
ALIGN TECHNOLOGY INC COM 016255101   1,739,500 10,000 SH Put SOLE   10,000 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206   4,094,400 1,023,600 SH Call SOLE   1,023,600 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206   600,000 150,000 SH Put SOLE   150,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103   15,465,000 60,000 SH Put SOLE   60,000 0 0
ZOGENIX INC COM NEW 98978L204   136,015 5,500 SH Call SOLE   5,500 0 0