Consolidated Statements of Stockholders' Equity - USD ($) shares in Thousands, $ in Thousands	Common Stock [Member]	Additional Paid-in Capital [Member]	AOCI Attributable to Parent [Member]	Retained Earnings [Member]	Total
Balance at Dec. 31, 2019	$ 5	$ 161,212		$ (79,061)	$ 82,156
Balance, shares at Dec. 31, 2019	47,658
Issuance of common stock in connection with underwritten public offering, net of issuance costs	$ 1	103,269			103,270
Issuance of common stock in connection with underwritten public offering, net of issuance costs, shares	7,590
Issuance of common stock in connection with at-the-market stock sales, net of issuance costs		9,869			9,869
Issuance of common stock in connection with at-the-market stock sales, net of issuance costs, shares	725
Issuance of common stock in connection with warrant exercises
Issuance of common stock in connection with warrant exercises, shares	326
Issuance of common stock in connection with stock option exercises		1,152			1,152
Issuance of common stock in connection with stock option exercises, shares	219
Unrealized loss on marketable securities, net of tax			(15)		(15)
Stock-based compensation		13,223			13,223
Net loss				(98,581)	(98,581)
Balance at Dec. 31, 2020	$ 6	288,725	(15)	(177,642)	111,074
Balance, shares at Dec. 31, 2020	56,518
Issuance of common stock in connection with underwritten public offering, net of issuance costs		102,329			102,329
Issuance of common stock in connection with underwritten public offering, net of issuance costs, shares	6,838
Issuance of common stock in connection with stock option exercises		48			$ 48
Issuance of common stock in connection with stock option exercises, shares	19				19
Unrealized loss on marketable securities, net of tax			(124)		$ (124)
Stock-based compensation		11,839			11,839
Net loss				(114,432)	(114,432)
Balance at Dec. 31, 2021	$ 6	402,941	(139)	(292,074)	110,734
Balance, shares at Dec. 31, 2021	63,375
Issuance of common stock in connection with at-the-market stock sales, net of issuance costs	$ 2	47,413			47,415
Issuance of common stock in connection with at-the-market stock sales, net of issuance costs, shares	10,307
Issuance of common stock in connection with warrant exercises
Issuance of common stock in connection with warrant exercises, shares	101
Issuance of common stock in connection with stock option exercises		1,036			$ 1,036
Issuance of common stock in connection with stock option exercises, shares	566				566
Unrealized loss on marketable securities, net of tax			(508)		$ (508)
Stock-based compensation		19,028			19,028
Net loss				(113,565)	(113,565)
Issuance of common stock in connection with private placement, net	$ 1	57,223			57,224
Issuance of common stock in connection with private placement, net, shares	13,319
Issuance of warrants in connection with debt issuance		485			485
Balance at Dec. 31, 2022	$ 9	$ 528,126	$ (647)	$ (405,639)	$ 121,849
Balance, shares at Dec. 31, 2022	87,668