Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands		Total	Follow-On Offering	At-The-Market Offering	Common Stock		Common Stock Follow-On Offering		Common Stock At-The-Market Offering		Additional Paid-In Capital	Additional Paid-In Capital Follow-On Offering	Additional Paid-In Capital At-The-Market Offering	Accumulated Deficit	Accumulated Other Comprehensive Loss
Beginning balance (in shares) at Dec. 31, 2021	[1]				3,020,034
Beginning balance at Dec. 31, 2021		$ 250,812			$ 5	[1]					$ 567,598			$ (316,615)	$ (176)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation expense		7,886									7,886
Issuance of common stock from at-the-market and follow-on public offerings (in shares)	[1]				4,694
Issuance of common stock from at-the-market and follow-on public offerings		1,368									1,368
Vesting of restricted stock units (in shares)	[1]				5,408
Shares withheld for taxes for vesting of restricted stock units (in shares)	[1]				(1,190)
Shares withheld for taxes for vesting of restricted stock units		(230)									(230)
Issuance of common stock upon exercise of stock options (in shares)	[1]				4,818
Issuance of common stock upon exercise of stock options		333									333
Change in unrealized loss on marketable securities, net of tax		(430)													(430)
Net loss		(68,717)												(68,717)
Ending balance (in shares) at Mar. 31, 2022	[1]				3,033,764
Ending balance at Mar. 31, 2022		191,022			$ 5	[1]					576,955			(385,332)	(606)
Beginning balance (in shares) at Dec. 31, 2021	[1]				3,020,034
Beginning balance at Dec. 31, 2021		250,812			$ 5	[1]					567,598			(316,615)	(176)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Change in unrealized loss on marketable securities, net of tax		3
Net loss		$ (214,029)
Ending balance (in shares) at Dec. 31, 2022		3,292,163			3,292,163	[2]
Ending balance at Dec. 31, 2022		$ 76,106			$ 5	[1]					606,918			(530,644)	(173)
Beginning balance (in shares) at Mar. 31, 2022	[1]				3,033,764
Beginning balance at Mar. 31, 2022		191,022			$ 5	[1]					576,955			(385,332)	(606)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation expense		7,611									7,611
Issuance of common stock from at-the-market and follow-on public offerings (in shares)	[1]				3,443
Issuance of common stock from at-the-market and follow-on public offerings		454									454
Vesting of restricted stock units (in shares)	[1]				424
Shares withheld for taxes for vesting of restricted stock units (in shares)	[1]				(148)
Shares withheld for taxes for vesting of restricted stock units		(17)									(17)
Issuance of common stock upon exercise of stock options (in shares)	[1]				876
Issuance of common stock upon exercise of stock options		67									67
Change in unrealized loss on marketable securities, net of tax		(74)													(74)
Net loss		(60,194)												(60,194)
Ending balance (in shares) at Jun. 30, 2022	[1]				3,038,359
Ending balance at Jun. 30, 2022		138,869			$ 5	[1]					585,070			(445,526)	(680)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation expense		6,730									6,730
Issuance of common stock from at-the-market and follow-on public offerings (in shares)	[1]				73,667
Issuance of common stock from at-the-market and follow-on public offerings		2,962									2,962
Vesting of restricted stock units (in shares)	[1]				354
Shares withheld for taxes for vesting of restricted stock units (in shares)	[1]				(109)
Shares withheld for taxes for vesting of restricted stock units		(6)									(6)
Issuance of common stock upon exercise of stock options (in shares)	[1]				12,016
Issuance of common stock upon exercise of stock options		409									409
Change in unrealized loss on marketable securities, net of tax		144													144
Net loss		(43,945)												(43,945)
Ending balance (in shares) at Sep. 30, 2022	[1]				3,124,287
Ending balance at Sep. 30, 2022		105,163			$ 5	[1]					595,165			(489,471)	(536)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock issuance costs		109
Stock-based compensation expense		6,366									6,366
Issuance of common stock from at-the-market and follow-on public offerings (in shares)	[1]				161,323
Issuance of common stock from at-the-market and follow-on public offerings		5,231									5,231
Issuance of common stock under employee stock purchase plan (in shares)	[1]				5,982
Issuance of common stock under employee stock purchase plan		163									163
Vesting of restricted stock units (in shares)	[1]				800
Shares withheld for taxes for vesting of restricted stock units (in shares)	[1]				(229)
Shares withheld for taxes for vesting of restricted stock units		(7)									(7)
Issuance of common stock upon exercise of stock options (in shares)	[1]				0
Issuance of common stock upon exercise of stock options		0									0
Change in unrealized loss on marketable securities, net of tax		363													363
Net loss		$ (41,173)												(41,173)
Ending balance (in shares) at Dec. 31, 2022		3,292,163			3,292,163	[2]
Ending balance at Dec. 31, 2022		$ 76,106			$ 5	[1]					606,918			(530,644)	(173)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation expense		7,593									7,593
Issuance of common stock from at-the-market and follow-on public offerings (in shares)	[2]				560,253
Issuance of common stock from at-the-market and follow-on public offerings		18,096			$ 1	[2]					18,095
Vesting of restricted stock units (in shares)	[2]				11,516
Shares withheld for taxes for vesting of restricted stock units (in shares)	[2]				(2,875)
Shares withheld for taxes for vesting of restricted stock units		(127)									(127)
Issuance of common stock upon exercise of stock options (in shares)	[2]				2,970
Issuance of common stock upon exercise of stock options		101									101
Change in unrealized loss on marketable securities, net of tax		154													154
Net loss		(37,455)												(37,455)
Ending balance (in shares) at Mar. 31, 2023	[2]				3,864,027
Ending balance at Mar. 31, 2023		$ 64,468			$ 6	[2]					632,580			(568,099)	(19)
Beginning balance (in shares) at Dec. 31, 2022		3,292,163			3,292,163	[2]
Beginning balance at Dec. 31, 2022		$ 76,106			$ 5	[1]					606,918			(530,644)	(173)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)		3,281
Change in unrealized loss on marketable securities, net of tax		$ 173
Net loss		$ (123,277)
Ending balance (in shares) at Dec. 31, 2023		8,791,877			8,791,877	[2]
Ending balance at Dec. 31, 2023		$ 69,669			$ 13	[2]					723,577			(653,921)	0
Beginning balance (in shares) at Mar. 31, 2023	[2]				3,864,027
Beginning balance at Mar. 31, 2023		64,468			$ 6	[2]					632,580			(568,099)	(19)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation expense		5,775									5,775
Issuance of common stock from at-the-market and follow-on public offerings (in shares)	[2]						4,296,646		392,541
Issuance of common stock from at-the-market and follow-on public offerings			$ 63,439	$ 6,032			$ 6	[2]	$ 1	[2]		$ 63,433	$ 6,031
Issuance of common stock under employee stock purchase plan (in shares)	[2]				15,663
Issuance of common stock under employee stock purchase plan		208									208
Vesting of restricted stock units (in shares)	[2]				720
Shares withheld for taxes for vesting of restricted stock units (in shares)	[2]				(249)
Shares withheld for taxes for vesting of restricted stock units		(4)									(4)
Change in unrealized loss on marketable securities, net of tax		19													19
Net loss		(34,312)												(34,312)
Ending balance (in shares) at Jun. 30, 2023	[2]				8,569,348
Ending balance at Jun. 30, 2023		105,625			$ 13	[2]					708,023			(602,411)	0
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock issuance costs		4,484
Stock-based compensation expense		5,763									5,763
Vesting of restricted stock units (in shares)	[2]				233
Shares withheld for taxes for vesting of restricted stock units (in shares)	[2]				(70)
Shares withheld for taxes for vesting of restricted stock units		(1)									(1)
Issuance of common stock upon exercise of stock options (in shares)	[2]				311
Issuance of common stock upon exercise of stock options		1									1
Net loss		(24,632)												(24,632)
Ending balance (in shares) at Sep. 30, 2023	[2]				8,569,822
Ending balance at Sep. 30, 2023		86,756			$ 13	[2]					713,786			(627,043)	0
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation expense		5,726									5,726
Issuance of common stock from at-the-market and follow-on public offerings (in shares)	[2]				212,453
Issuance of common stock from at-the-market and follow-on public offerings		3,964									3,964
Issuance of common stock under employee stock purchase plan (in shares)	[2]				9,027
Issuance of common stock under employee stock purchase plan		106									106
Vesting of restricted stock units (in shares)	[2]				824
Shares withheld for taxes for vesting of restricted stock units (in shares)	[2]				(249)
Shares withheld for taxes for vesting of restricted stock units		(5)									(5)
Net loss		$ (26,878)												(26,878)
Ending balance (in shares) at Dec. 31, 2023		8,791,877			8,791,877	[2]
Ending balance at Dec. 31, 2023		$ 69,669			$ 13	[2]					$ 723,577			$ (653,921)	$ 0
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock issuance costs		$ 123

[1] Results have been retroactively adjusted to reflect the 1-for-15 reverse stock split effected on November 28, 2023. See Note 2 for details.

[2] Results have been retroactively adjusted to reflect the 1-for-15 reverse stock split effected on November 28, 2023. See Note 2 for details.