Commitments and Contingencies - Licenses to Patented Technology (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Commitments and Contingencies Disclosure [Abstract]
Consideration paid	$ 635	$ 641	$ 7
Purchase Commitment, Excluding Long-term Commitment [Line Items]
Consideration paid	635	641	7
Cost of sales	5,416	$ 2,617	$ 8
National Institute of Allergy and Infectious Diseases member | License agreement
Purchase Commitment, Excluding Long-term Commitment [Line Items]
Cost of sales	$ 400