CONDENSED CONSOLIDATED STATEMENTS OF INCOME - USD ($) shares in Millions, $ in Millions	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Revenue:
Total revenue	$ 6,066	$ 1,937
Operating expenses:
Cost of sales	1,017	193
Research and development	554	401
Selling, general and administrative	268	77
Total operating expenses	1,839	671
Income from operations	4,227	1,266
Interest income	15	4
Other expense, net	(13)	(10)
Income before income taxes	4,229	1,260
Provision for income taxes	572	39
Net income	$ 3,657	$ 1,221
Earnings per share:
Basic (usd per share)	$ 9.09	$ 3.05
Diluted (usd per share)	$ 8.58	$ 2.84
Weighted average common shares used in calculation of earnings per share:
Basic (in shares)	402	400
Diluted (in shares)	426	430
Product sales
Revenue:
Total revenue	$ 5,925	$ 1,733
Grant revenue
Revenue:
Total revenue	126	194
Collaboration revenue
Revenue:
Total revenue	$ 15	$ 10