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Other Balance Sheet Components - Accrued Liabilities (Details) - USD ($)
$ in Thousands
Dec. 31, 2020
Dec. 31, 2019
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Clinical trials $ 97,249 $ 6,291
Compensation-related 95,247 27,428
Raw materials 78,085 0
Manufacturing 53,412 5,872
Development operations 29,253 2,567
Property and equipment 17,576 4,029
Commercial 6,922 0
Other external goods and services 91,847 21,465
Accrued liabilities $ 469,591 $ 67,652