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Commitments and Contingencies - Strategic Collaborations (Details) - PCV Agreement - USD ($)
$ in Millions
Jun. 30, 2019
Dec. 31, 2018
Jun. 30, 2016
Research and Development Arrangement, Contract to Perform for Others [Line Items]      
Budgeted amount     $ 250.0
PCV products      
Research and Development Arrangement, Contract to Perform for Others [Line Items]      
Budgeted amount $ 243.0 $ 243.0