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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Cash flows from operating activities:    
Net loss $ (25,973) $ (17,103)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization expense 283 190
Stock-based compensation expense 2,822 1,455
Deferred rent expense (53) (40)
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 976 (1,485)
Other assets 319  
Accounts payable (1,443) 671
Accrued expenses and other current liabilities 635 (1,426)
Net cash used in operating activities (22,434) (17,738)
Cash flows from investing activities:    
Purchases of property and equipment (577) (340)
Net cash used in investing activities (577) (340)
Cash flows from financing activities:    
Proceeds from exercise of stock options 35 252
Proceeds from issuance of common shares upon completion of public offering, net of offering costs 93,628  
Net cash provided by financing activities 93,663 252
Net increase (decrease) in cash, cash equivalents and restricted cash 70,652 (17,826)
Cash, cash equivalents and restricted cash at beginning of period 187,535 126,794
Cash, cash equivalents and restricted cash at end of period 258,187 108,968
Supplemental disclosure of non-cash investing and financing activities:    
Property and equipment held for sale   336
Offering costs included in accrued expenses and accounts payable 249  
Reconciliation of cash, cash equivalents and restricted cash reported within the condensed consolidated balance sheets:    
Cash and cash equivalents 257,695 108,476
Long-term restricted cash (included in other assets) 492 492
Cash, cash equivalents and restricted cash at end of period $ 258,187 $ 108,968