Nature of the Business - Additional Information (Detail) - USD ($) $ in Thousands	3 Months Ended
Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022
Net loss	$ (24,957)	$ (29,833)
Accumulated deficit	(514,389)		$ (489,432)
Cash and cash equivalents	$ 72,326	$ 161,663	$ 92,563

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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+ Details