Stock-Based Compensation (Tables)

3 Months Ended

Mar. 31, 2023

Share-Based Payment Arrangement [Abstract]

Summary of Assumptions that Used to Determine Grant-Date Fair Value of Stock Options Granted to Employees and Members of Board of Directors

The assumptions that the Company used to determine the grant-date fair value of stock options granted to employees and members of the board of directors were as follows, presented on a weighted-average basis:

	Three Months Ended March 31,
	2022
Expected option life (years)		6.00
Risk-free interest rate		1.67	%
Expected volatility		80.19	%
Expected dividend yield		—	%

Summary of Stock Option Activity

The following table summarizes the Company’s stock option activity for the three months ended March 31, 2023:

	Number of Options			Weighted- Average Exercise Price		Weighted- Average Remaining Contractual Term (Years)		Aggregate Intrinsic Value
Outstanding as of December 31, 2022		9,423,271		$	7.26		8.14	$	22
Granted		—		$	—
Exercised		(45,999	)	$	0.91
Cancelled or forfeited		(222,503	)	$	3.73
Outstanding as of March 31, 2023		9,154,769		$	7.38		7.82	$	446
Exercisable as of March 31, 2023		3,855,390		$	11.44		6.32	$	56

Summary of Restricted Common Stock Units

The following table summarizes the Company’s restricted common stock units for the three months ended March 31, 2023:

	Number of Shares			Weighted- Average Grant Date Fair Value
Issued and unvested as of December 31, 2022		940,392		$	3.62
Granted		1,286,550		$	1.68
Vested		(104,813	)	$	1.85
Forfeited, cancelled or expired		(95,791	)	$	2.13
Issued and unvested as of March 31, 2023		2,026,338		$	2.55

Schedule of Stock-based Compensation Expense

Stock-based compensation expense was allocated as follows:

	Three Months Ended March 31,
	2023		2022
Research and development	$	622	$	939
General and administrative		1,908		2,439
Total stock-based compensation expense	$	2,530	$	3,378