Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Operating expenses:
Research and development	$ 15,919	$ 23,043	$ 54,049	$ 64,114
General and administrative	7,066	9,577	26,128	26,765
Total operating expenses	22,985	32,620	80,177	90,879
Loss from operations	(22,985)	(32,620)	(80,177)	(90,879)
Other (expense) income:
Interest income (expense), net	111	2	(544)	21
Other (expense) income, net	(95)	5	(135)	(41)
Total other income (expense), net	16	7	(679)	(20)
Net loss and comprehensive loss	$ (22,969)	$ (32,613)	$ (80,856)	$ (90,899)
Net loss per share - basic	$ (0.52)	$ (0.75)	$ (1.85)	$ (2.13)
Net loss per share - diluted	$ (0.52)	$ (0.75)	$ (1.85)	$ (2.13)
Weighted-average number of common shares outstanding - basic	43,773	43,623	43,722	42,588
Weighted-average number of common shares outstanding - diluted	43,773	43,623	43,722	42,588