Nature of the Business - Additional Information (Detail) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Net loss	$ (28,054)	$ (31,387)	$ (57,887)	$ (58,286)
Accumulated deficit	(441,429)		(441,429)		$ (383,542)
Cash and cash equivalents	$ 132,409	$ 226,438	$ 132,409	$ 226,438	$ 189,567