Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Income Statement [Abstract]
Collaboration revenue	$ 6,342	$ 19,163
Operating expenses:
Research and development	76,782	69,701
General and administrative	41,694	30,516
Restructuring expenses	427
Total operating expenses	118,903	100,217
Loss from operations	(112,561)	(81,054)
Other income, net	2,690	207
Net loss	$ (109,871)	$ (80,847)
Earnings Per Share, Basic	$ (2.44)	$ (2.29)
Earnings Per Share, Diluted	$ (2.44)	$ (2.29)
Weighted Average Number of Shares Outstanding, Diluted	44,991	35,361
Weighted Average Number of Shares Outstanding, Basic	44,991	35,361
Comprehensive loss:
Net loss	$ (109,871)	$ (80,847)
Other comprehensive loss:
Unrealized loss on marketable securities	(400)	(395)
Total other comprehensive loss	(400)	(395)
Comprehensive loss	$ (110,271)	$ (81,242)