COMMON STOCK WARRANTS (Tables)

12 Months Ended

Dec. 31, 2022

Equity [Abstract]

Schedule of common stock warrant activity

The following is the activity for common stock warrants:

Issue Date	Warrant Type	Term Date	Exercise Price		Balance December 31, 2020	Issued	Exercised	Expired	Balance December 31, 2021	Issued	Exercised	Expired	Balance December 31, 2022
November 2017	Common Stock Offering	November 2022	$	27.32	7,175	—	(1,089)	—	6,086	—	—	(6,086)	—
June 2018	Reissue	December 2023	$	728.00	2,835	—	—	—	2,835	—	—	—	2,835
August 2018	Rights Offering	July 2023	$	460.00	10,149	—	(25)	—	10,124	—	—	—	10,124
August 2018	Dealer Manager	August 2023	$	690.00	670	—	—	—	670	—	—	—	670
July 2019	Dealer Manager	July 2024	$	675.00	419	—	—	—	419	—	—	—	419
January 2020	Registered Direct Offering	July 2025	$	180.00	8,761	—	—	—	8,761	—	—	—	8,761
January 2020	Dealer Manager	July 2025	$	200.00	667	—	—	—	667	—	—	—	667
March 2020	Dealer Manager	March 2025	$	75.13	664	—	—	—	664	—	—	—	664
April 2020	Dealer Manager	April 2025	$	79.40	5,906	—	—	—	5,906	—	—	—	5,906
April 2020	Registered Direct Offering	April 2025	$	61.00	2,500	—	—	—	2,500	—	—	—	2,500
October 2020	Private Inducement	April 2026	$	34.500	35,034	—	(35,034)	—	—	—	—	—	—
October 2020	Private Inducement	November 2027	$	3.165	50,000	—	—	—	50,000	—	—	—	50,000
October 2020	Dealer Manager	April 2026	$	43.12	4,254	—	—	—	4,254	—	—	—	4,254
February 2021	Private Placement Agreement	August 2026	$	44.32	—	82,300	—	—	82,300	—	—	—	82,300
February 2021	Private Placement Agreement	November 2027	$	3.165	—	27,430	—	—	27,430	—	—	—	27,430
February 2021	Dealer Manager	August 2026	$	56.96	—	16,460	—	—	16,460	—	—	—	16,460
March 2021	Dealer Manager	March 2026	$	50.00	—	7,408	—	—	7,408	—	—	—	7,408
November 2022	Pre-Funded Warrants	February 2023	$	3.50	—	—	—	—	—	1,361,000	(131,000)	—	1,230,000
November 2022	Series A	November 2027	$	3.165	—	—	—	—	—	1,428,572	—	—	1,428,572
November 2022	Series B	December 2023	$	3.165	—	—	—	—	—	1,428,572	—	—	1,428,572
November 2022	Dealer Manager	November 2027	$	4.375	—	—	—	—	—	107,143	—	—	107,143
					129,034	133,598	(35,059)	—	226,484	4,325,287	(131,000)	—	4,414,685

As of December 31, 2022, we had 4,414,685 shares of common stock issuable upon exercise of outstanding common stock warrants, at a weighted-average exercise price of $6.58 per share and expiring as follows:

	Weighted Average Exercise Price		Shares
Years Ending December 31:
2023	$	5.99	2,672,201
2024	675.00		419
2025	128.75		18,498
2026	46.54		110,422
2027	3.25		1,613,145
	6.58		4,414,685

Schedule of common stock warrant expiration information

The following is the activity for common stock warrants:

Issue Date	Warrant Type	Term Date	Exercise Price		Balance December 31, 2020	Issued	Exercised	Expired	Balance December 31, 2021	Issued	Exercised	Expired	Balance December 31, 2022
November 2017	Common Stock Offering	November 2022	$	27.32	7,175	—	(1,089)	—	6,086	—	—	(6,086)	—
June 2018	Reissue	December 2023	$	728.00	2,835	—	—	—	2,835	—	—	—	2,835
August 2018	Rights Offering	July 2023	$	460.00	10,149	—	(25)	—	10,124	—	—	—	10,124
August 2018	Dealer Manager	August 2023	$	690.00	670	—	—	—	670	—	—	—	670
July 2019	Dealer Manager	July 2024	$	675.00	419	—	—	—	419	—	—	—	419
January 2020	Registered Direct Offering	July 2025	$	180.00	8,761	—	—	—	8,761	—	—	—	8,761
January 2020	Dealer Manager	July 2025	$	200.00	667	—	—	—	667	—	—	—	667
March 2020	Dealer Manager	March 2025	$	75.13	664	—	—	—	664	—	—	—	664
April 2020	Dealer Manager	April 2025	$	79.40	5,906	—	—	—	5,906	—	—	—	5,906
April 2020	Registered Direct Offering	April 2025	$	61.00	2,500	—	—	—	2,500	—	—	—	2,500
October 2020	Private Inducement	April 2026	$	34.500	35,034	—	(35,034)	—	—	—	—	—	—
October 2020	Private Inducement	November 2027	$	3.165	50,000	—	—	—	50,000	—	—	—	50,000
October 2020	Dealer Manager	April 2026	$	43.12	4,254	—	—	—	4,254	—	—	—	4,254
February 2021	Private Placement Agreement	August 2026	$	44.32	—	82,300	—	—	82,300	—	—	—	82,300
February 2021	Private Placement Agreement	November 2027	$	3.165	—	27,430	—	—	27,430	—	—	—	27,430
February 2021	Dealer Manager	August 2026	$	56.96	—	16,460	—	—	16,460	—	—	—	16,460
March 2021	Dealer Manager	March 2026	$	50.00	—	7,408	—	—	7,408	—	—	—	7,408
November 2022	Pre-Funded Warrants	February 2023	$	3.50	—	—	—	—	—	1,361,000	(131,000)	—	1,230,000
November 2022	Series A	November 2027	$	3.165	—	—	—	—	—	1,428,572	—	—	1,428,572
November 2022	Series B	December 2023	$	3.165	—	—	—	—	—	1,428,572	—	—	1,428,572
November 2022	Dealer Manager	November 2027	$	4.375	—	—	—	—	—	107,143	—	—	107,143
					129,034	133,598	(35,059)	—	226,484	4,325,287	(131,000)	—	4,414,685

As of December 31, 2022, we had 4,414,685 shares of common stock issuable upon exercise of outstanding common stock warrants, at a weighted-average exercise price of $6.58 per share and expiring as follows:

	Weighted Average Exercise Price		Shares
Years Ending December 31:
2023	$	5.99	2,672,201
2024	675.00		419
2025	128.75		18,498
2026	46.54		110,422
2027	3.25		1,613,145
	6.58		4,414,685