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Revenue Recognition - Summary of Revenue Disaggregated by Research Program (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Disaggregation Of Revenue [Line Items]    
Total collaboration revenue $ 50,931 $ 27,941
MAT2A Program    
Disaggregation Of Revenue [Line Items]    
Total collaboration revenue 29,756 7,230
Pol Theta Program    
Disaggregation Of Revenue [Line Items]    
Total collaboration revenue 13,894 12,894
WRN Program    
Disaggregation Of Revenue [Line Items]    
Total collaboration revenue $ 7,281 $ 7,817