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Related Party Transactions - Additional Information (Detail) - USD ($)
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Dec. 31, 2015
Investors [Member] | Series A-3 Redeemable Convertible Preferred Shares [Member]          
Related Party Transaction [Line Items]          
Legal and consulting costs     $ 200,000    
Dr. Emmanuelle Charpentier [Member] | TRACR Hematology Limited [Member]          
Related Party Transaction [Line Items]          
Noncontrolling interest in TRACR     17.90%    
Payment of consulting, licensing and other fees $ 17,000 $ 8,000 $ 1,000,000 $ 25,000  
Related party transaction additional fees     300,000   $ 1,000,000
Bayer Healthcare LLC [Member]          
Related Party Transaction [Line Items]          
Revenue related to research and development services $ 400,000 $ 0 $ 400,000 $ 0