Stock-based compensation (Tables)

12 Months Ended

Dec. 31, 2022

Share-Based Payment Arrangement [Abstract]

Schedule of Allocation of Share based Compensation

Total stock-based compensation expense related to all of the Company’s stock-based awards was recorded in the consolidated statements of operations and comprehensive loss as follows (in thousands):

	For the Years Ended December 31,
	2022		2021
Research and development	$	4,734	$	4,637
Selling, general and administrative	7,924		5,971
Total stock-based compensation expense	$	12,658	$	10,608

Schedule of Nonvested Share Activity

Activity for the restricted shares is shown below:

	Number of shares
Unvested as of December 31, 2021	2,585,670
Repurchased	(789,846)
Vested	(782,516)
Unvested as of December 31, 2022	1,013,308

Activity for the phantom units is shown below:

	Number of Units	Weighted Average Strike Price
Unvested as of December 31, 2020	1,202,435	$	0.47
Granted	—	—
Vested	—	—
Exchange of Phantom Units for Cash Payment Rights, SARs, and/or Stock Options	(1,202,435)	$	0.47
Unvested as of December 31, 2021	—	$	—

Schedule of Stock Option Activity

Activity for stock options is shown below:

	Number of Options	Weighted Average Exercise Price per Share		Weighted Average Remaining Contractual Term (in years)	Aggregate Intrinsic Value (in thousands $)
Outstanding at December 31, 2021	7,757,401	$	3.72	9.2	$	40,939
Granted	7,679,043	5.40
Exercised	(537,078)	1.26
Canceled/ Forfeited	(3,192,316)	5.22
Expired	(277,651)	5.84
Outstanding at December 31, 2022	11,429,399	4.49		8.4	2,949
Exercisable at December 31, 2022	3,008,380	$	3.03	6.9	$	2,058
Vested and expected to vest as of December 31, 2022	11,429,399			8.4	$	2,949

Schedule of Determination of Fair Value

The estimated grant-date fair value of all the Company’s stock options was calculated using the Black-Scholes option pricing model, based on the following assumptions:

	For the Years Ended December 31,
	2022	2021
Expected term (in years)	5.5-6.1	3.5-6.1
Volatility	63%-65%	45%-47%
Risk-free interest rate	1.6%-4.2%	0.3%-1.5%
Dividend Yield	—%	—%