Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the reference to our firm under the caption “Experts” and to the use of our report dated February 14, 2020, in the Registration Statement (Form S-1) and related Prospectus of IMARA Inc. dated February 14, 2020.

/s/ Ernst & Young LLP

Boston, Massachusetts

February 14, 2020