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Accounting policies, General information (Details)
1 Months Ended 12 Months Ended
Feb. 05, 2022
GBP (£)
Jul. 31, 2022
GBP (£)
shares
Jul. 31, 2022
USD ($)
shares
Dec. 31, 2022
ClinicalStageProgram
shares
General information [Abstract]        
Proceeds from shares issued   £ 116,812,000 $ 140,000,000  
Offering expenses   £ 388,000    
Number of clinical stage programs | ClinicalStageProgram       4
Ordinary Shares [Member]        
General information [Abstract]        
Number of shares issued (in shares) | shares   3,733,333 3,733,333 20
IPO [Member]        
General information [Abstract]        
Proceeds from shares issued £ 210,985,000