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Note 15 - Share-based Compensation (Tables)
9 Months Ended
Sep. 30, 2022
Notes Tables  
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
   

Three Months Ended

   

Nine Months Ended

 
   

September 30,

   

September 30,

 
   

2022

   

2021

   

2022

   

2021

 

Research and development expenses

  $ 642     $ 971     $ 2,040     $ 3,119  

Selling, general and administrative expenses

    1,798       4,544       6,172       14,637  
    $ 2,440     $ 5,515     $ 8,212     $ 17,756