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Income Taxes - Additional Information (Details) - USD ($)
3 Months Ended 6 Months Ended 9 Months Ended 12 Months Ended
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Jun. 30, 2019
Jun. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Operating Loss Carryforwards [Line Items]                              
Income tax provision $ 31,000 $ 136,000 $ 258,000 $ 208,000 $ 1,079,000 $ (3,000) $ 128,000 $ 333,000 $ 466,000 $ 461,000 $ 602,000 $ 458,000 $ 633,000 $ 1,537,000 $ 636,000
Net loss before income taxes (70,980,000) $ (56,641,000) $ (86,668,000) $ (108,544,000) (119,032,000) $ (84,435,000) $ (60,382,000) $ (25,890,000) $ (195,212,000) $ (86,272,000) $ (251,853,000) $ (170,707,000) $ (322,833,000) $ (289,739,000) $ (294,392,000)
Effective income tax rate                         (0.20%) (0.50%) (0.20%)
Valuation allowance 633,591,000       571,277,000               $ 633,591,000 $ 571,277,000  
Increase (decrease) in valuation allowance                         62,300,000 24,000,000  
Uncertain tax positions increase                         4,200,000    
Unrecognized tax benefits that would result in adjustments to the valuation allowance 31,500,000                       31,500,000    
Interest and penalties accrued 0       $ 0               0 $ 0  
Domestic Tax Authority                              
Operating Loss Carryforwards [Line Items]                              
Operating loss carryforwards 1,800,000,000                       1,800,000,000    
Operating loss carryforwards, subject to expiration 1,700,000,000                       1,700,000,000    
Operating loss carryforwards, not subject to expiration 100,000,000                       100,000,000    
State and Local Jurisdiction                              
Operating Loss Carryforwards [Line Items]                              
Operating loss carryforwards 1,600,000,000                       1,600,000,000    
Research Tax Credit Carryforward | Domestic Tax Authority                              
Operating Loss Carryforwards [Line Items]                              
Tax credit carryforwards 20,500,000                       20,500,000    
Research Tax Credit Carryforward | State and Local Jurisdiction                              
Operating Loss Carryforwards [Line Items]                              
Tax credit carryforwards 14,000,000                       14,000,000    
Investment Tax Credit Carryforward | Domestic Tax Authority                              
Operating Loss Carryforwards [Line Items]                              
Tax credit carryforwards $ 6,600,000                       $ 6,600,000