Document Format Files
| Seq | Description | Document | Type | Size |
|---|---|---|---|---|
| 1 | S-1/A | d528918ds1a.htm | S-1/A | 2132500 |
| 2 | EX-1.1 | d528918dex11.htm | EX-1.1 | 256933 |
| 3 | EX-3.1 | d528918dex31.htm | EX-3.1 | 30310 |
| 4 | EX-3.3 | d528918dex33.htm | EX-3.3 | 6792 |
| 5 | EX-3.4 | d528918dex34.htm | EX-3.4 | 76143 |
| 6 | EX-4.1 | d528918dex41.htm | EX-4.1 | 6535 |
| 7 | EX-5.1 | d528918dex51.htm | EX-5.1 | 5867 |
| 8 | EX-10.1 | d528918dex101.htm | EX-10.1 | 305796 |
| 9 | EX-10.2 | d528918dex102.htm | EX-10.2 | 263993 |
| 10 | EX-10.3 | d528918dex103.htm | EX-10.3 | 70827 |
| 11 | EX-10.5 | d528918dex105.htm | EX-10.5 | 32516 |
| 12 | EX-10.6 | d528918dex106.htm | EX-10.6 | 46418 |
| 13 | EX-10.8 | d528918dex108.htm | EX-10.8 | 79030 |
| 14 | EX-10.9 | d528918dex109.htm | EX-10.9 | 59934 |
| 15 | EX-10.10 | d528918dex1010.htm | EX-10.10 | 31513 |
| 16 | EX-10.11 | d528918dex1011.htm | EX-10.11 | 20161 |
| 17 | EX-10.12 | d528918dex1012.htm | EX-10.12 | 16725 |
| 18 | EX-10.13 | d528918dex1013.htm | EX-10.13 | 49647 |
| 19 | EX-10.14 | d528918dex1014.htm | EX-10.14 | 48742 |
| 20 | EX-10.15 | d528918dex1015.htm | EX-10.15 | 47503 |
| 21 | EX-23.1 | d528918dex231.htm | EX-23.1 | 1934 |
| 22 | GRAPHIC | g528918dsp007.jpg | GRAPHIC | 421282 |
| 23 | GRAPHIC | g528918dsp008.jpg | GRAPHIC | 191991 |
| 24 | GRAPHIC | g528918g06m15.jpg | GRAPHIC | 106715 |
| 25 | GRAPHIC | g528918g09s33.jpg | GRAPHIC | 51291 |
| 26 | GRAPHIC | g528918g10i27.jpg | GRAPHIC | 33816 |
| 27 | GRAPHIC | g528918g18p37.jpg | GRAPHIC | 118857 |
| 28 | GRAPHIC | g528918g18s45.jpg | GRAPHIC | 148965 |
| 29 | GRAPHIC | g528918g20p40.jpg | GRAPHIC | 41919 |
| 30 | GRAPHIC | g528918g22g10.jpg | GRAPHIC | 37725 |
| 31 | GRAPHIC | g528918g22t20.jpg | GRAPHIC | 46716 |
| 32 | GRAPHIC | g528918g25u87.jpg | GRAPHIC | 43151 |
| 33 | GRAPHIC | g528918g37s43.jpg | GRAPHIC | 81715 |
| 34 | GRAPHIC | g528918g38q12.jpg | GRAPHIC | 58694 |
| 35 | GRAPHIC | g528918g39i69.jpg | GRAPHIC | 43471 |
| 36 | GRAPHIC | g528918g39u19.jpg | GRAPHIC | 88912 |
| 37 | GRAPHIC | g528918g40i63.jpg | GRAPHIC | 154315 |
| 38 | GRAPHIC | g528918g45d96.jpg | GRAPHIC | 50441 |
| 39 | GRAPHIC | g528918g48l38.jpg | GRAPHIC | 61404 |
| 40 | GRAPHIC | g528918g55a18.jpg | GRAPHIC | 40412 |
| 41 | GRAPHIC | g528918g57y60.jpg | GRAPHIC | 168959 |
| 42 | GRAPHIC | g528918g58b45.jpg | GRAPHIC | 141573 |
| 43 | GRAPHIC | g528918g58y37.jpg | GRAPHIC | 70309 |
| 44 | GRAPHIC | g528918g88t20.jpg | GRAPHIC | 49346 |
| 45 | GRAPHIC | g528918g89g54.jpg | GRAPHIC | 41897 |
| 46 | GRAPHIC | g528918g89k11.jpg | GRAPHIC | 88505 |
| 47 | GRAPHIC | g528918g93t48.jpg | GRAPHIC | 3037 |
| 48 | GRAPHIC | g528918g97i45.jpg | GRAPHIC | 45532 |
| Complete submission text file | 0001193125-18-295666.txt | 6936363 |
IRS No.: 471514975 | State of Incorp.: DE | Fiscal Year End: 1231
Type: S-1/A | Act: 33 | File No.: 333-227523 | Film No.: 181112945
SIC: 2836 Biological Products, (No Diagnostic Substances)
