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Property and equipment (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Dec. 31, 2023
Property Plant And Equipment [Line Items]          
Property and equipment $ 15,079   $ 15,079   $ 14,895
Less: accumulated depreciation (8,873)   (8,873)   (7,763)
Total property and equipment, net 6,206   6,206   7,132
Depreciation expense 365 $ 447 1,109 $ 1,450  
Laboratory equipment          
Property Plant And Equipment [Line Items]          
Property and equipment 8,213   8,213   8,042
Leasehold improvements          
Property Plant And Equipment [Line Items]          
Property and equipment 4,712   4,712   4,712
Furniture and fixtures          
Property Plant And Equipment [Line Items]          
Property and equipment 1,435   1,435   1,422
Office equipment          
Property Plant And Equipment [Line Items]          
Property and equipment 621   621   621
Computer equipment          
Property Plant And Equipment [Line Items]          
Property and equipment $ 98   $ 98   $ 98