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Collaboration and license agreements - Schedule of revenue from collaboration agreements (Details) - USD ($)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]    
Revenue from collaboration agreements $ 20,756,000 $ 31,096,000
Roche Agreement    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]    
Revenue from collaboration agreements 9,063,000 4,939,000
Biogen Agreement    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]    
Revenue from collaboration agreements 10,623,000 19,214,000
Calico Agreement    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]    
Revenue from collaboration agreements 1,070,000 6,943,000
Betta Agreement    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]    
Revenue from collaboration agreements $ 0 $ 0