Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Income Statement [Abstract]
Revenue from collaboration agreements	$ 31,096	$ 45,785
Operating expenses:
Research and development	117,841	94,665
General and administrative	42,789	33,254
Total operating expenses	160,630	127,919
Loss from operations	(129,534)	(82,134)
Other income (expense), net
Interest expense and amortization of long-term debt—related party	(2,216)	(2,145)
Interest and other income, net	3,575	387
Total other income (expense), net	1,359	(1,758)
Net loss	$ (128,175)	$ (83,892)
Net loss per share — basic (in dollars per share)	$ (2.62)	$ (1.82)
Net loss per share — diluted (in dollars per share)	$ (2.62)	$ (1.82)
Weighted-average number of shares - basic (in shares)	48,861,665	46,041,733
Weighted-average number of shares - diluted (in shares)	48,861,665	46,041,733
Other Comprehensive loss:
Unrealized loss on marketable securities	$ (3,362)	$ (788)
Comprehensive loss	$ (131,537)	$ (84,680)
Revenue from Contract with Customer, Product and Service [Extensible Enumeration]	Collaborative Arrangement [Member]	Collaborative Arrangement [Member]