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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Cash flows from operating activities:    
Net loss $ (57,215) $ (29,991)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:    
Depreciation 1,289 684
Stock-based compensation expense 2,623 277
Accretion on short-term investments (1,589) (85)
Loss on disposal of property and equipment 127  
Change in fair value associated with convertible preferred stock tranche liability   876
Changes in operating assets and liabilities:    
Prepaid expense and other current assets (5,003) (1,463)
Accounts payable 4,383 1,720
Accrued expenses and other liabilities 3,042 864
Deferred revenue (252) 33,411
Deferred rent 10,033 186
Net cash (used in) provided by operating activities (42,562) 6,479
Cash flows from investing activities:    
Purchases of short-term investments (245,328) (78,071)
Maturities of short-term investments 148,480  
Purchases of property and equipment (24,939) (1,958)
Changes in restricted cash   (1,497)
Net cash used in investing activities (121,787) (81,526)
Cash flows from financing activities:    
Proceeds from issuance of common stock in initial public offering, net of discounts and issuance costs 150,843  
Proceeds from issuance of common stock from option exercises 87  
Proceeds from issuance of restricted common stock 64  
Repurchase of unvested common stock   (17)
Net cash provided by financing activities 150,994 115,230
Net change in cash and cash equivalents (13,355) 40,183
Cash and cash equivalents, beginning of period 51,575 11,392
Cash and cash equivalents, end of period 38,220 51,575
Supplemental disclosures of noncash investing and financing activities:    
Reclassification of liability for common stock vested 75 225
Property and equipment additions included in accounts payable 9,127 167
Deferred offering costs included in accrued expenses   1,000
Reclassification of tranche liability upon issuance of convertible preferred stock   5,123
Series A Convertible Preferred Stock    
Cash flows from financing activities:    
Proceeds from issuance of convertible preferred stock, net of issuance costs   20,479
Series A Convertible Preferred Stock | Initial Public Offering    
Supplemental disclosures of noncash investing and financing activities:    
Conversion of convertible preferred stock into common stock upon initial public offering 42,994  
Series B Convertible Preferred Stock    
Cash flows from financing activities:    
Proceeds from issuance of convertible preferred stock, net of issuance costs   $ 94,768
Series B Convertible Preferred Stock | Initial Public Offering    
Supplemental disclosures of noncash investing and financing activities:    
Conversion of convertible preferred stock into common stock upon initial public offering $ 94,768