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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Cash flows from operating activities:    
Net income (loss) $ 29,290 $ (62,181)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 997 6,280
Noncash lease expense 969 869
Loss from equity method investment 4,131 0
Stock-based compensation expense 9,965 12,582
(Amortization of premium) accretion of discount on short-term investments (872) 664
Loss on disposal of property and equipment 6
Gain on sale of business (131,249) 0
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (5,301) (2,133)
Accounts payable 2,711 (1,123)
Accrued expenses and other liabilities 5,672 225
Deferred revenue (2,406) (32,609)
Operating lease liabilities (369) (1,901)
Net cash used in operating activities (86,462) (79,321)
Cash flows from investing activities:    
Purchases of short-term investments (157,460) (97,391)
Maturities of short-term investments 47,461 5,000
Proceeds from sale of business 130,000
Purchases of property and equipment (1,276) (2,058)
Net cash provided by (used in) investing activities 18,725 (94,449)
Cash flows from financing activities:    
Proceeds from issuance of common stock in follow-on public offering, net of discounts and issuance costs 49,744
Proceeds From Issuance Of Common Stock Pursuant To ATM Financing Net Of Discounts And Issuance Costs 1,454
Proceeds from issuance of common stock pursuant to employee stock purchase plan 563 825
Proceeds from issuance of common stock from option exercises 1 145
Net cash provided by financing activities 564 52,168
Net change in cash, cash equivalents and restricted cash (67,173) (121,602)
Cash, cash equivalents and restricted cash, beginning of period 110,335 218,705
Cash, cash equivalents and restricted cash, end of period 43,162 97,103
Supplemental disclosures of noncash investing and financing activities:    
Reclassification of liability for common stock vested 12
Property and equipment additions included in accounts payable 34
Property and equipment additions included in accrued expenses and other liabilities 8
Unrealized gain (loss) on available for sale securities, net $ (450) $ (5)