CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (Unaudited) - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning balance at Dec. 31, 2020	$ 261,968	$ 6	$ 543,842	$ 5	$ (281,885)
Beginning balance, Shares at Dec. 31, 2020		61,860,897
Issuance of common stock under employee stock compensation plans	360		360
Issuance of common stock under employee stock compensation plans, Shares		265,839
Stock-based compensation expense	3,462		3,462
Unrealized gain (loss) on available-for-sale investments	10			10
Net income (loss)	(38,314)				(38,314)
Ending balance at Mar. 31, 2021	227,486	$ 6	547,664	15	(320,199)
Ending balance, Shares at Mar. 31, 2021		62,126,736
Beginning balance at Dec. 31, 2020	261,968	$ 6	543,842	5	(281,885)
Beginning balance, Shares at Dec. 31, 2020		61,860,897
Unrealized gain (loss) on available-for-sale investments	(5)
Net income (loss)	(126,443)
Ending balance at Sep. 30, 2021	150,157	$ 6	558,479		(408,328)
Ending balance, Shares at Sep. 30, 2021		62,469,819
Beginning balance at Mar. 31, 2021	227,486	$ 6	547,664	15	(320,199)
Beginning balance, Shares at Mar. 31, 2021		62,126,736
Issuance of common stock under employee stock compensation plans	67		67
Issuance of common stock under employee stock compensation plans, Shares		39,431
Stock-based compensation expense	4,742		4,742
Unrealized gain (loss) on available-for-sale investments	(14)			(14)
Net income (loss)	(45,705)				(45,705)
Ending balance at Jun. 30, 2021	186,576	$ 6	552,473	1	(365,904)
Ending balance, Shares at Jun. 30, 2021		62,166,167
Issuance of common stock under employee stock compensation plans	1,855		1,855
Issuance of common stock under employee stock compensation plans, Shares		303,652
Stock-based compensation expense	4,151		4,151
Unrealized gain (loss) on available-for-sale investments	(1)			(1)
Net income (loss)	(42,424)				(42,424)
Ending balance at Sep. 30, 2021	150,157	$ 6	558,479		(408,328)
Ending balance, Shares at Sep. 30, 2021		62,469,819
Beginning balance at Dec. 31, 2021	156,211	$ 6	563,064		(406,859)
Beginning balance, Shares at Dec. 31, 2021		62,523,596
Issuance of common stock under employee stock compensation plans	681		681
Issuance of common stock under employee stock compensation plans, Shares		181,130
Stock-based compensation expense	4,867		4,867
Net income (loss)	(58,057)				(58,057)
Ending balance at Mar. 31, 2022	103,702	$ 6	568,612		(464,916)
Ending balance, Shares at Mar. 31, 2022		62,704,726
Beginning balance at Dec. 31, 2021	156,211	$ 6	563,064		(406,859)
Beginning balance, Shares at Dec. 31, 2021		62,523,596
Unrealized gain (loss) on available-for-sale investments	(144)
Net income (loss)	(30,684)
Ending balance at Sep. 30, 2022	216,313	$ 9	653,991	(144)	(437,543)
Ending balance, Shares at Sep. 30, 2022		85,946,414
Beginning balance at Mar. 31, 2022	103,702	$ 6	568,612		(464,916)
Beginning balance, Shares at Mar. 31, 2022		62,704,726
Issuance of common stock under employee stock compensation plans	32		32
Issuance of common stock under employee stock compensation plans, Shares		24,000
Stock-based compensation expense	5,234		5,234
Unrealized gain (loss) on available-for-sale investments	(132)			(132)
Net income (loss)	(43,036)				(43,036)
Ending balance at Jun. 30, 2022	65,800	$ 6	573,878	(132)	(507,952)
Ending balance, Shares at Jun. 30, 2022		62,728,726
Issuance of common stock under employee stock compensation plans	540		540
Issuance of common stock under employee stock compensation plans, Shares		217,688
Issuance of common stock from public offering	75,299	$ 3	75,296
Issuance of common stock from public offering, net of issuance costs, Shares		23,000,000
Stock-based compensation expense	4,277		4,277
Unrealized gain (loss) on available-for-sale investments	(12)			(12)
Net income (loss)	70,409				70,409
Ending balance at Sep. 30, 2022	$ 216,313	$ 9	$ 653,991	$ (144)	$ (437,543)
Ending balance, Shares at Sep. 30, 2022		85,946,414