Collaboration and License Agreements - Summary of Reconciliation of Closing Balance of Deferred Revenue Related to agreements (Details) - USD ($) $ in Thousands	9 Months Ended	12 Months Ended
	Sep. 30, 2022	Dec. 31, 2021
Collaborations And License Agreement [Line Items]
Beginning balance	$ 13,762
Amounts received/invoiced	148,698	$ 45,000
Revenue recognized	(120,441)	(31,238)
Ending balance	42,019	13,762
Roche Collaboration Agreement
Collaborations And License Agreement [Line Items]
Amounts received/invoiced	146,533
Revenue recognized	(114,109)
Ending balance	32,424
Takeda Collaboration Agreement
Collaborations And License Agreement [Line Items]
Beginning balance	13,762
Amounts received/invoiced	2,165	45,000
Revenue recognized	(6,332)	(31,238)
Ending balance	$ 9,595	$ 13,762