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Commitments and Contingencies - Additional Information (Details)
$ in Thousands
1 Months Ended 12 Months Ended
Oct. 24, 2019
USD ($)
Aug. 03, 2018
USD ($)
Apr. 28, 2017
USD ($)
Aug. 03, 2015
USD ($)
Oct. 31, 2019
USD ($)
Jul. 31, 2019
USD ($)
Oct. 31, 2018
USD ($)
Mar. 31, 2016
USD ($)
Installment
Dec. 31, 2020
USD ($)
ft²
Option
Dec. 31, 2019
USD ($)
Jan. 01, 2020
USD ($)
Oct. 25, 2019
USD ($)
Commitments And Contingencies [Line Items]                        
Operating leases, number of square feet | ft²                 83,000      
Operating leases remaining lease terms                 108 months      
Operating lease, option to extend, description                 The manufacturing and laboratory and office space lease agreements include two options to extend the term for a period of 5 years each.      
Operating lease, option to extend                 true      
Operating lease, extended term                 5 years      
Operating lease, number of options to extend term | Option                 2      
Operating lease, commencement date         Jul. 29, 2020 Jun. 26, 2020 Apr. 01, 2019 Jun. 30, 2016        
Operating lease, initial term               10 years 6 months        
Security deposit         $ 300 $ 100   $ 100        
Operating lease, termination date               Apr. 30, 2019        
Operating lease, termination fee               $ 1,500        
Operating lease, termination fee, number of installments | Installment               3        
Operating lease, termination fee, term               1 year 6 months        
Operating lease, expiration date         Dec. 31, 2029 Dec. 31, 2029 Dec. 31, 2029          
Tenant improvements           $ 2,900 $ 4,200          
Additional tenant reimbursements         $ 1,500              
Operating lease right-of-use assets                 $ 24,986      
Initial lease liability                 30,182      
Accumulated deficit                 281,885 $ 152,221    
Operating lease expense                 6,000 $ 2,500    
Operating lease, payments                 $ 4,800      
Operating lease, weighted-average remaining lease term                 8 years 8 months 12 days      
Operating lease, weighted-average discount rate                 8.90%      
License Agreement | Janssen Biotech Inc.                        
Commitments And Contingencies [Line Items]                        
Upfront fee       $ 200                
Milestone payments                 $ 4,000      
Initial milestone payments payable                 75,800      
Additional milestone payments payable                 $ 46,800      
License Agreement | Genus Oncology, LLC                        
Commitments And Contingencies [Line Items]                        
Upfront fee $ 1,500                      
Initial milestone payments payable                       $ 71,000
Additional fee payable to exercise option $ 1,500                      
Commercial License Agreement | TeneoBio, Inc.                        
Commitments And Contingencies [Line Items]                        
Upfront fee   $ 4,000 $ 500                  
Initial milestone payments payable     20,500                  
Additional milestone payments payable     $ 20,500                  
Milestone payments payable   $ 31,000                    
ASC 842                        
Commitments And Contingencies [Line Items]                        
Operating lease, option to extend, description                 The leases in San Diego include an option to extend, which was not recognized as part of the lease liability and ROU lease assets as the Company was not reasonably certain it would exercise the extension right.      
Operating lease, option to extend                 true      
Initial lease receivables                     $ 2,700  
Operating lease right-of-use assets                     22,300  
Deferred rent balance                     2,300  
Initial lease liability                     27,300  
ASC 842 | Cumulative Adjustment                        
Commitments And Contingencies [Line Items]                        
Accumulated deficit                     100  
Other Current Assets                        
Commitments And Contingencies [Line Items]                        
Receivable for amounts to be reimbursed                 $ 100      
Property and Equipment                        
Commitments And Contingencies [Line Items]                        
Tenant improvements                 $ 13,300      
Property and Equipment | ASC 842 | Adoption of ASC 842 Adjustment                        
Commitments And Contingencies [Line Items]                        
Derecognition of construction in progress related to manufacturing facility                     2,100  
Other Long-Term Liabilities | ASC 842 | Adoption of ASC 842 Adjustment                        
Commitments And Contingencies [Line Items]                        
Derecognition of construction financing obligation related to manufacturing facility                     2,500  
Prepaid and Other Current Assets | ASC 842 | Adoption of ASC 842 Adjustment                        
Commitments And Contingencies [Line Items]                        
Derecognition of other receivables related to manufacturing facility                     $ 300  
Maximum                        
Commitments And Contingencies [Line Items]                        
Operating lease remaining lease term dedicated to manufacturing suites                 12 months