Strategic Investment - Additional Information (Details) - USD ($)		1 Months Ended	12 Months Ended
	Aug. 04, 2023	Aug. 31, 2022	Dec. 31, 2023	Dec. 31, 2022
Strategic Investment [Line Items]
Common stock, par value			$ 0.0001	$ 0.0001
Aggregate gross proceeds			$ 928,000
Non-refundable upfront payment	$ 35,600,000
Revenue recognized			(64,703,000)	$ (130,492,000)
Common Stock
Strategic Investment [Line Items]
Sale of stock, number of shares issued		23,000,000
Sale of stock, price per share		$ 3.5
Aggregate gross proceeds		$ 75,300,000
Astellas
Strategic Investment [Line Items]
Revenue recognized			0
Deferred revenue recognized			$ 35,600,000
Securities Purchase Agreement | Astellas | Common Stock
Strategic Investment [Line Items]
Discount for lack of marketability of shares, at fair value on date of issuance	$ 14,400,000
Securities Purchase Agreement | Astellas | Private Placement | Common Stock
Strategic Investment [Line Items]
Sale of stock, number of shares issued	8,333,333
Common stock, par value	$ 0.0001
Sale of stock, price per share	$ 3
Aggregate gross proceeds	$ 25,000,000
Astellas Strategic Rights Letter Agreement | Astellas
Strategic Investment [Line Items]
Proceeds from rights granted	$ 25,000,000
Maximum number of shares owned at time of termination	8,000,000
Discount for lack of marketability of shares, at fair value on date of issuance	$ 14,400,000
Proceeds from shares allocated to non-refundable upfront payment	$ 10,600,000