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STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Cash flows from operating activities:    
Net loss $ (69,389) $ (36,603)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation, amortization and other 7,196 3,413
Stock-based compensation 10,288 7,911
Changes in operating assets and liabilities:    
Prepaid expenses and other assets (4,889) 559
Accounts payable (1,959) 2,040
Accrued liabilities (178) (244)
Deferred rent 1,687 348
Deferred revenue   (22,378)
Net cash used in operating activities (57,244) (44,954)
Cash flows from investing activities:    
Maturities of marketable securities 195,438 187,784
Purchases of marketable securities (156,477) (137,129)
Purchase of property and equipment (2,360) (7,132)
Net cash provided by investing activities 36,601 43,523
Cash flows from financing activities:    
Proceeds from exercise of stock options 208 112
Payments of the term loan (3,473) (1,527)
Net cash used in financing activities (3,265) (1,415)
Net decrease in cash, cash equivalents and restricted cash (23,908) (2,846)
Cash, cash equivalents and restricted cash - beginning of period 36,284 39,130
Cash, cash equivalents and restricted cash - end of period 12,376 36,284
Supplemental disclosures of cash flow information:    
Cash paid for interest $ 162 130
Supplemental disclosures of noncash investing and financing activities:    
Purchase of property and equipment included in accrued liabilities   $ 109