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Note 6 - Equity - Stock based Compensation (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Stock-based compensation expense $ 2,275 $ 2,373
General and Administrative Expense [Member]    
Stock-based compensation expense 1,467 1,461
Research and Development Expense [Member]    
Stock-based compensation expense $ 808 $ 912