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Note 5 - Equity - Stock based Compensation (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Stock-based compensation expense $ 433 $ 408 $ 838 $ 805
General and Administrative Expense [Member]        
Stock-based compensation expense 332 329 641 664
Research and Development Expense [Member]        
Stock-based compensation expense $ 101 $ 79 $ 197 $ 141