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Leases - Additional Information (Details)
3 Months Ended 9 Months Ended
Apr. 27, 2020
USD ($)
ft²
Aug. 26, 2019
Mar. 22, 2019
USD ($)
ft²
Mar. 05, 2019
USD ($)
ft²
Sep. 30, 2020
USD ($)
ft²
Sep. 30, 2019
USD ($)
Sep. 30, 2020
USD ($)
ft²
Sep. 30, 2019
USD ($)
Dec. 31, 2019
USD ($)
Lessee Lease Description [Line Items]                  
Sublease income         $ 337,000 $ 0 $ 495,000 $ 0  
Cash paid for amounts included in measurement of operating lease liabilities             $ 4,600,000    
Operating lease, weighted-average remaining lease term         9 years 2 months 12 days   9 years 2 months 12 days    
Operating lease, weighted-average discount rate         10.30%   10.30%    
Operating lease costs         $ 1,206,000 $ 1,700,000 $ 3,627,000 $ 3,700,000  
500 Technology Square                  
Lessee Lease Description [Line Items]                  
Area of lease | ft²         19,823   19,823    
Lease, base rent per year             $ 1,500,000    
Increase in annual rent percentage         2.50%   2.50%    
Lease commencement date             Dec. 28, 2016    
Original lease expiration date             Dec. 31, 2021    
Accelerated lease expiration date   Feb. 28, 2020              
Tenant improvement allowance         $ 1,200,000   $ 1,200,000    
500 Technology Square | Letters of Credit                  
Lessee Lease Description [Line Items]                  
Security deposit         400,000   $ 400,000    
4 Hartwell Place                  
Lessee Lease Description [Line Items]                  
Area of lease | ft²       18,707          
Lease, base rent per year       $ 900,000          
Increase in annual rent percentage       3.00%          
Lease expiration month and year       2029-12          
Lease commencement month and year       2019-07          
Lessee, operating lease, existence of option to extend [true false]       true          
Lessee, operating lease, option to extend             The Company has the option to extend the lease twice, each for a 5-year period, on the same terms and conditions as the current lease, subject to a change in base rent based on market rates.    
Lessee, operating lease, option to extend term       5 years          
Tenant improvement allowance, received         1,100,000   $ 1,100,000    
4 Hartwell Place | Maximum                  
Lessee Lease Description [Line Items]                  
Tenant improvement allowance       $ 1,300,000          
4 Hartwell Place | Letters of Credit                  
Lessee Lease Description [Line Items]                  
Security deposit       $ 400,000          
35 Cambridge Park Drive                  
Lessee Lease Description [Line Items]                  
Area of lease | ft²     68,258            
Lease, base rent per year     $ 4,900,000            
Increase in annual rent percentage     3.00%            
Lease commencement date     Mar. 26, 2019            
Original lease expiration date     Nov. 30, 2029            
Tenant improvement allowance     $ 12,300,000            
Lessee, operating lease, existence of option to extend [true false]     true            
Lessee, operating lease, option to extend             The Company has the option to extend the lease for a 10-year period on the same terms and conditions as the current lease, subject to a change in base rent based on market rates.    
Lessee, operating lease, option to extend term     10 years            
Tenant improvement allowance, received         12,200,000   $ 12,200,000    
Construction oversight fee     2.00%            
Area of space for sublease | ft² 23,280                
Sublease payments to be received annually $ 1,300,000                
Sublease income, increase in annual percentage 3.00%                
Sublease commencement date May 18, 2020                
Sublease expiration month and year 2022-05                
Lessee, operating sublease, existence of option to extend true                
Lessee, operating sublease, option to extend             The sublessee has the option to extend the sublease for a one-year period on the same terms and conditions as the current sublease, subject to a change in base rent based on the greater of (i) an increase of 3% of the annual rent owed by the sublessee in year two, and (ii) market rent for the subleased premises.    
Lessee, operating sublease, option to extend term 1 year                
35 Cambridge Park Drive | Other Income                  
Lessee Lease Description [Line Items]                  
Sublease income         300,000   $ 500,000    
35 Cambridge Park Drive | Letters of Credit                  
Lessee Lease Description [Line Items]                  
Security deposit         $ 3,700,000   $ 3,700,000   $ 3,700,000
Security deposit in connection with sublease $ 300,000