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Income Taxes - Schedule of Reconciliation of Income Tax Expense (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Income Tax Disclosure [Abstract]      
Expected income tax benefit at federal statutory rate $ (45,051) $ (34,423) $ (22,605)
State income tax benefit, net of federal benefit (797) (128) (7,083)
Change in valuation allowance 59,951 39,733 34,495
R&D credit (18,179) (10,918) (7,117)
Stock-based compensation 1,241 781 1,196
Australian tax incentive 35 266 27
State rate change 44 3,243 (8)
Uncertain tax positions 2,691 0 0
Other 65 1,446 1,095
Provision for income taxes $ 0 $ 0 $ 0