Consolidated Statements of Shareholders’ Equity - USD ($) $ in Thousands	Total	At-The-Market Sales Agreement	Ordinary shares	Ordinary shares At-The-Market Sales Agreement	Additional paid-in capital	Additional paid-in capital At-The-Market Sales Agreement	Ordinary shares held in treasury	Accumulated other comprehensive loss	Accumulated deficit
Beginning balance (in shares) at Dec. 31, 2021			489,177,550
Beginning balance at Dec. 31, 2021	$ 148,005		$ 31,855		$ 385,070		$ (603)	$ (4,601)	$ (263,716)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(24,837)								(24,837)
Issuance of common shares (in shares)				80,696
Issuance of common shares		$ 67		$ 5		$ 62
Restricted share units vested							186		(186)
Issuance of ordinary shares to treasury (in shares)			4,800,000
Issuance of ordinary shares to treasury	0		$ 322				(322)
Common shares withheld for taxes on vested stock awards	(793)				(793)
Equity settled share-based compensation reclassified as cash-settled	118				118
Share-based compensation	3,747				3,747
Ending balance (in shares) at Mar. 31, 2022			494,058,246
Ending balance at Mar. 31, 2022	126,307		$ 32,182		388,204		(739)	(4,601)	(288,739)
Beginning balance (in shares) at Dec. 31, 2021			489,177,550
Beginning balance at Dec. 31, 2021	148,005		$ 31,855		385,070		(603)	(4,601)	(263,716)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(42,603)
Ending balance (in shares) at Jun. 30, 2022			494,058,246
Ending balance at Jun. 30, 2022	110,880		$ 32,182		390,543		(591)	(4,601)	(306,653)
Beginning balance (in shares) at Mar. 31, 2022			494,058,246
Beginning balance at Mar. 31, 2022	126,307		$ 32,182		388,204		(739)	(4,601)	(288,739)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(17,766)								(17,766)
Restricted share units vested							148		(148)
Common shares withheld for taxes on vested stock awards	(689)				(689)
Equity settled share-based compensation reclassified as cash-settled	(25)				(25)
Share-based compensation	3,053				3,053
Ending balance (in shares) at Jun. 30, 2022			494,058,246
Ending balance at Jun. 30, 2022	$ 110,880		$ 32,182		390,543		(591)	(4,601)	(306,653)
Beginning balance (in shares) at Dec. 31, 2022	606,301,054		631,338,246
Beginning balance at Dec. 31, 2022	$ 230,466		$ 40,526		529,187		(1,549)	(4,601)	(333,097)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(16,743)								(16,743)
Issuance of common shares (in shares)			20,321,384
Issuance of common shares	56,909		$ 1,227		55,682
Restricted share units vested							270		(270)
Share options exercised	1,827				1,756		71
Share-based compensation	4,290				4,290
Ending balance (in shares) at Mar. 31, 2023			651,659,630
Ending balance at Mar. 31, 2023	$ 276,749		$ 41,753		590,915		(1,208)	(4,601)	(350,110)
Beginning balance (in shares) at Dec. 31, 2022	606,301,054		631,338,246
Beginning balance at Dec. 31, 2022	$ 230,466		$ 40,526		529,187		(1,549)	(4,601)	(333,097)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	$ (25,550)
Ending balance (in shares) at Jun. 30, 2023	635,787,302		651,659,630
Ending balance at Jun. 30, 2023	$ 273,093		$ 41,753		596,059		(975)	(4,601)	(359,143)
Beginning balance (in shares) at Mar. 31, 2023			651,659,630
Beginning balance at Mar. 31, 2023	276,749		$ 41,753		590,915		(1,208)	(4,601)	(350,110)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(8,807)								(8,807)
Restricted share units vested							226		(226)
Share options exercised	77				70		7
Share-based compensation	$ 5,074				5,074
Ending balance (in shares) at Jun. 30, 2023	635,787,302		651,659,630
Ending balance at Jun. 30, 2023	$ 273,093		$ 41,753		$ 596,059		$ (975)	$ (4,601)	$ (359,143)