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Share based compensation - Weighted-Average Assumptions (Details) - Share Options - $ / shares
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Risk-free interest rate, minimum 2.09% 0.79%
Risk-free interest rate, maximum 4.20% 1.32%
Expected volatility, minimum 82.50% 85.35%
Expected volatility, maximum 84.27% 87.68%
Expected dividend yield 0.00% 0.00%
Minimum    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected lives, years 5 years 5 years
Grant date fair value (in dollars per share) $ 0.34 $ 0.62
Maximum    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected lives, years 7 years 7 years
Grant date fair value (in dollars per share) $ 1.33 $ 0.78