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Accrued expenses (Details) - USD ($)
$ in Thousands
Mar. 31, 2021
Dec. 31, 2020
Payables and Accruals [Abstract]    
Clinical trial and other development costs $ 6,536 $ 8,607
Professional fees and general corporate costs 1,454 2,149
People related costs 524 107
Total accrued expenses $ 8,514 $ 10,863