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Summary of Significant Accounting Policies - Additional Information (Detail)
$ in Thousands
3 Months Ended 12 Months Ended
Sep. 20, 2018
Dec. 31, 2018
USD ($)
Sep. 30, 2018
USD ($)
Jun. 30, 2018
USD ($)
Mar. 31, 2018
USD ($)
Dec. 31, 2017
USD ($)
Sep. 30, 2017
USD ($)
Jun. 30, 2017
USD ($)
Mar. 31, 2017
USD ($)
Dec. 31, 2018
USD ($)
Dec. 31, 2017
USD ($)
Dec. 31, 2016
USD ($)
Jan. 01, 2019
USD ($)
Summary Of Significant Accounting Policies [Line Items]                          
Reverse stock split 0.1449                        
Accumulated deficit   $ 126,402       $ 61,627       $ 126,402 $ 61,627    
Net loss   $ 17,338 $ 18,588 $ 15,473 $ 13,376 17,368 $ 9,451 $ 7,790 $ 6,768 64,775 41,377 $ 18,750  
Net cash used in operating activities                   38,162 34,971 15,292  
Impairment losses                   $ 0 0 $ 0  
Lessor financed improvement incentives due but not yet received           $ 1,200         $ 1,200    
Percentage of realized upon ultimate settlement                   50.00%      
Accounting Standards Update 2016-02 [Member] | Subsequent Event [Member]                          
Summary Of Significant Accounting Policies [Line Items]                          
Lease, right-of-use asset                         $ 14,200
Lease liability                         11,200
Derecognition of deferred rent                         1,800
Derecognition of building and related accumulated depreciation                         14,500
Derecognition of financing lease obligation                         $ 10,500