Collaboration and License Agreements - Schedule of Changes in Deferred Revenue Balance (Detail) $ in Thousands	12 Months Ended
	Dec. 31, 2023 USD ($)
Gilead [Member]
Deferred Revenue
Balance at December 31, 2022	$ 100
Balance at December 31, 2023	100
2 Seventy [Member]
Deferred Revenue
Balance at December 31, 2022	1,000
Research Collaboration and License Agreement [Member] | 2 Seventy [Member]
Deferred Revenue
Balance at December 31, 2022	1,047
Additions	0
Deductions	(1,047)
Balance at December 31, 2023	0
Collaboration, Option and License Agreement [Member] | Gilead [Member]
Deferred Revenue
Balance at December 31, 2022	107
Additions	0
Deductions	(56)
Balance at December 31, 2023	51
Funding Agreement [Member] | CEPI [Member]
Deferred Revenue
Balance at December 31, 2022	2,952
Additions	3,634
Deductions	(4,295)
Balance at December 31, 2023	2,291
Grant Agreement [Member] | Gates Foundation [Member]
Deferred Revenue
Balance at December 31, 2022	1,025
Additions	700
Deductions	(1,717)
Balance at December 31, 2023	$ 8